Other medicines and Delay Spray

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This is particularly important if you are taking the following medicines which may interact with Delay Spray:

other local anesthetics
heart medicines (antiarrhythmic medicines)
medicines for high blood pressure and to regulate your heart rhythm ( beta blockers)
medicines reducing your stomach acid (cimetidine)

The risk of a disorder reducing the amount of oxygen in the blood (methemoglobinemia) may be increased if you are already taking medicines known to cause the condition, such as those listed below:

Benzocaine – a local anesthetic used to treat pain and itching
Chloroquine, pamaquine, primaquine, quinine - used to treat malaria
Metoclopramide – used to treat feelings of sickness (nausea) and vomiting, including in patients with migraine
Glyceryl trinitrate (GTN, nitroglycerin), isosorbide mononitrate, erythrityl tetranitrate, pentaerythritol tetranitrate and other nitrate and nitrite medicines - used to treat angina (chest pain caused by the heart)
Sodium nitroprusside, isosorbide dinitrate – used to treat high blood pressure and heart failure
Nitrofurantoin – an antibiotic used to treat urinary and kidney infections
Sulfonamides (also called sulfa medicines) i.e. sulfamethoxazole – an antibiotic used to treat urinary infections, and sulfasalazine – used to treat Crohn’s disease, ulcerative colitis and rheumatoid arthritis
Dapsone – used to treat skin conditions such as leprosy and dermatitis and also to prevent malaria and pneumonia in high-risk patients
Phenobarbital, phenytoin – used to treat epilepsy
Para-aminosalicylic acid (PAS) – used to treat tuberculosis

The risk of methemoglobinemia can also be increased by the use of certain dyes (aniline dyes), or the pesticide naphthalene, so let your doctor know if you work with any dyes or chemical pesticides.
Any barrier contraceptives (i.e. male or female condom), which are made from polyurethane-based material cannot be guaranteed to protect against disease or pregnancy when you are also using Delay Spray. Check the material that your contraceptive or your partner’s contraceptive is made of. Ask your pharmacist if you are unsure.

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